CORO1A CLIA Kit for Human(Homo sapiens) | EIAab.comCORO1A CLIA Kit for Human(Homo sapiens)

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Index > Protein center > CORO1A(Gene name) > Human

CORO1A (Gene name),

Coronin-1A (Protein name ), COR1A_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CORO1A(CORO1);

Protein name:

Coronin-1A;

Alternative:

Coronin-like protein p57;Coronin-like protein A(Clipin-A);Tryptophan aspartate-containing coat protein(TACO);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds actin.

Function:

May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.

Subcellular Location:

Cytoplasm cytoskeleton Cytoplasm cell cortex Cytoplasmic vesicle phagosome membrane In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification.

Protein Attributes:

Sequence length:

461

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

461:

LDRLEETVQA | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P31146

MIM:

605000

Pfam:

PF08953

STRING:

9606.ENSP00000219150

String:

P31146

UniGene:

Hs.415067

KEGG:

hsa:11151

Uniprot:

P31146

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ELISA Kit for Human Coronin-1A

Cat.:

E0023m

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Packing:

96T

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ELISA Kit for Human Coronin-1A

Cat.:

E0023r

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96T

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ELISA Kit for Human Coronin-1A

Cat.:

E0023h

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96T

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ELISA Kit for Human Coronin-1A

Cat.:

E0023b

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Packing:

96T

CLIA Kit for Human Coronin-1A

Cat.:

U0023b

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MSDS:

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Packing:

96T

CLIA Kit for Human Coronin-1A

Cat.:

U0023h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Coronin-1A

Cat.:

U0023m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Coronin-1A

Cat.:

U0023r

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human Coronin-1A

Cat.:

P0023Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Coronin-1A

Cat.:

P0023Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Coronin-1A

Cat.:

P0023Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Coronin-1A

Protein for Human Coronin-1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular cloning of a novel actin-binding protein, p57, with a WD repeat and a leucine zipper motif."
Suzuki K. , Nishihata J. , Arai Y. , Honma N. , Yamamoto K. , Irimura T. , Toyoshima S.
FEBS Lett.364:283-288(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Peripheral blood leukocyte.
2.

Grogan A. , Keep N.H. , Reeves E. , Segal A.W.
Submitted (1995-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

Liau G. , Popa I. , Argraves K. , Argraves W.S.
Submitted (1995-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Kidney.
4.

"A new therapeutic strategy of mycobacterium infection by use of anti-TACO sequence."
Kohchi C. , Inagawa H. , Makino K. , Terada H. , Soma G.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thymus.
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
8.

Bienvenut W.V. , Kanor S. , Tissot J.-D. , Quadroni M.
Submitted (2006-05) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-9; 50-65; 242-252; 433-448 AND 453-460;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: T-cell.
9.

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Rasmussen H.H. , van Damme J. , Puype M. , Gesser B. , Celis J.E. , Vandekerckhove J.
Electrophoresis13:960-969(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 355-374
tissue: Keratinocyte.
10.

"A coat protein on phagosomes involved in the intracellular survival of mycobacteria."
Ferrari G. , Langen H. , Naito M. , Pieters J.
Cell97:435-447(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN PHAGOSOME TRAFFICKING
11.

"Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion."
Shiow L.R. , Paris K. , Akana M.C. , Cyster J.G. , Sorensen R.U. , Puck J.M.
Clin. Immunol.131:24-30(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IMD8
12.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
13.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-449;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A."
Ichikawa D. , Mizuno M. , Yamamura T. , Miyake S.
J. Biol. Chem.286:43465-43474(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION BY RNF128
16.

"Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin."
Oku T. , Nakano M. , Kaneko Y. , Ando Y. , Kenmotsu H. , Itoh S. , Tsuiji M. , Seyama Y. , Toyoshima S. , Tsuji T.
J. Biol. Chem.287:42910-42920(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-2 AND THR-412;INTERACTION WITH ACTIN
17.

"Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation."
Moshous D. , Martin E. , Carpentier W. , Lim A. , Callebaut I. , Canioni D. , Hauck F. , Majewski J. , Schwartzentruber J. , Nitschke P. , Sirvent N. , Frange P. , Picard C. , Blanche S. , Revy P. , Fischer A. , Latour S. , Jabado N. , more...
J. Allergy Clin. Immunol.131:1594-1603(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD8 MET-134;CHARACTERIZATION OF VARIANT IMD8 MET-134

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